An Unbiased View of conolidine
These outcomes, together with a former report exhibiting that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like habits in mice,two support the strategy of targeting ACKR3 as a novel approach to modulate the opioid process, which could open new therapeutic avenues for opioid-similar Problems.Morphine and various opioids enhance the acti